Cells and Their Organelles

When using a microscope to magnify a section of tissue from any organism, you will observe that it is composed of units known as cells. The cell is a basic structural and functional unit of an organism.

Cells are visible in the epithelium tissue of the mammalian gut (left) and onion root hair tip (right) Image sources (from left to right): Berkshire Community College Bioscience Image Library - Epithelial Tissues: Mucous Glands in Simple Columnar Epithelium, CC0, https://commons.wikimedia.org/w/index.php?curid=70159512 Johnathan Gutierrez, CC BY-SA 4.0, https://creativecommons.org/licenses/by-sa/4.0

Multicellular organisms, such as animals and plants, exhibit a complex organisation. For instance, the human body is comprised of approximately 30 trillion cells. In contrast, some organisms, like amoebae, consist of a single cell. Cells come in various shapes and sizes, each equipped with specialised functions that contribute to the overall functioning of living systems. Different functions of a cell can be assigned to specialised compartments called organelles.

Some types of mammalian cells Image sources (from left to right): UC Regents Davis campus - http://brainmaps.org, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=22012513 Electron Microscopy Facility at The National Cancer Institute at Frederick (NCI-Frederick) - [1], Public Domain, https://commons.wikimedia.org/w/index.php?curid=407197 CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=600755 SubtleGuest at English Wikipedia, CC BY 2.5, https://commons.wikimedia.org/w/index.php?curid=19688924

Cells can be categorised as eukaryotic or prokaryotic. Two large groups of organisms, bacteria and archaea have prokaryotic cells, while all other organisms have eukaryotic cells. Take a look at the diagram below and try to identify two major similarities and one difference between prokaryotic and eukaryotic cells.

Bacterial (prokaryotic) cell on the left and animal (eukaryotic) cell on the right. Image source: Biorender.com

All cells share common characteristics, one of the most notable being the presence of a plasma membrane and ribosomes. The cell membrane serves to control what goes in and out of the cell. The ribosomes perform the synthesis of proteins.

The major difference is the presence of a nucleus and other membrane-enclosed organelles in eukaryotic cells. Membranes separate such organelles from the rest of the cell in order to maintain conditions (e.g. pH or concentration of some molecules) optimised to perform particular tasks. A jelly-like substance surrounding the organelles is called cytosol.

Animal cell Image source: Biorender.com

The functions of major organelles that can be found in most eukaryotic cells are described in the table below.

Organelle
Function

Nucleus

Stores most of the cell’s genetic material

Mitochondrion

The site of aerobic respiration, the process that produces adenosine triphosphate (ATP) – a molecule that cells use as a major source of energy

Ribosome

Makes proteins

Rough endoplasmic reticulum

Is covered by ribosomes. Transports proteins to other parts of the cell

Smooth endoplasmic reticulum

Makes lipids, stores calcium ions, breaks toxins

Golgi apparatus

Modifies proteins and packages them into vesicles

Lysosome

Digests molecules

Cytoskeleton

A network of protein filaments that defines the cell shape, enables the cell movement and intracellular transport

Plant cell Image source: Biorender.com

Plant cells have some organelles distinguishing them from animal cells.

Plant cell organelle
Function

Permanent vacuole

Contains the cell sap which stores degradative enzymes, waste products and inorganic ions

Chloroplast

Glucose is synthesised here in course of photosynthesis

Cell wall

A rigid structure surrounding the cell which protects the cell and defines its shape

Prokaryotic cells have no nucleus and other membrane-bound organelles. Many prokaryotes are surrounded by two membranes (gram-negative bacteria).

Bacterial cell Image source: Biorender.com
Bacterial cell organelle
Function

Nucleoid

A region where the bacterial chromosome is located

Plasmid

Small circular DNA that often carries genes for antibiotic resistance

Flagellum

An organelle responsible for movement

Summary

The video below provides a summary of the topic and some additional details:

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